Features
It includes in this first release 1103 proteins, of which 812 are enzymes.
Only 241 human proteins were already present in other datasets of multifunctional proteins
(Moon DB,
MoonProt, and MultitaskProtDB II,
which when restricted to humans collect 47, 103, and 185 proteins, respectively).
Other proteins are derived from recent literature. Enzymes with multiple EC codes are included.
MultifacetedProtDB increases by four times the number of multifunctional proteins reported in currently available resources.
For each protein the search allows retrieving structural and functional features alongside with inclusion in biological pathways and disease associations when present.
How to browse
In the search bar, the user may insert a specific query, having as input:
- Gene name
- UniProt accession number or protein name
- Disease (MONDO, OMIM, Orphanet, ICD-10 or disease name
- Phenotypes (HPO ID or name)
- Sucellular location, Cell or tissue of expression
- EC number, Reactome (ID or name)
- GO term (ID or name)
- Pfam Interpro (ID or name)